ncRNA name | hsa-miR-125b |
ncRNA Category | miRNA |
Disease name | age-related macular degeneration (AMD) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cells |
Methods | NA |
Expression pattern | up-regulated |
Functional description | Restoration of HK2 in H2O2 treated RPE cells prevents the oxidative stress-suppressed glucose metabolism. Inhibition of the H2O2-induced miR-125b by inhibitor significantly prevented disorders of glucose metabolism. |
PubMed ID | 29631677 |
Year | 2018 |
Title | Inhibition of the oxidative stress-induced miR-125b protects glucose metabolic disorders of human retinal pigment epithelium (RPE) cells. |
Drug-related ncRNA | NO |
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